About

We investigate the problem of assessing the functional coherence of set of bio-molecules in a formal framework. SetSim is a statistically motivated functional similarity measure that takes into account functional specificity as well as distribution of attributes.

Algorithms

The technical underpinnings and algorithms for SetSim are described in the article below:

J. Pandey, M. Koyuturk, S. Subramaniam, A. Grama, Functional coherence in domain interaction networks, 7th European Conf. Computational Biology, pubmed.

J. Pandey, M. Koyuturk, A. Grama, Functional Characterization and Topological Modularity of Molecular Interaction Networks, APBC 2010, in press.

Download

Requires Java 1.5 or higher. Libraries required : JUNG 1.7.6, Collections-Generic 3.2, Collections-CLI 1.1, Cern Colt Scientific Library 1.2.0.

Binaries (all required libraries included) : download
Source Code : Project Files

Contact

Please direct all questions, suggestions and bug reports to jpandey [ AT ] cs [DOT] purdue [DOT] edu