Assistant Professor of Computer Science
Assistant Professor of Biological Sciences
Joined department in 2003
Education:
BS, Biochemistry
University of Tokyo (1994)
MS, Bioinformatics
Kyoto University (1996)
PhD, Bioinformatics
Kyoto University (1999)
Dr. Kihara's research interest is in the area of bioinformatics. In the last decade, a large amount
of biological data, such as genome/protein sequences, protein 3D structures, and pathway data have
become available. This data now enables us to employ comprehensive analysis of relationship between
protein sequence, structure and function, evolution of protein families, pathways, and organisms.
Especially, he is focusing on developing computational methods to predict and analyze protein
structure/function, pathway structure, and their applications in genome-scale or pathway/network
scale. He has worked recently on protein structure prediction, protein global/local shape comparison,
development of prediction method of transmembrane proteins, and its application to genome sequences.
Selected Publications
Troy Hawkins, Stan Luban and Daisuke Kihara, "Enhanced automated function prediction using distantly
related sequences and contextual association by PFP", Protein Science, Volume 15, 1550-1556,
2006.
Yen Hock Tan, He Huang, Daisuke Kihara, "Statistical potential-based amino acid similarity matrices
for aligning distantly related protein sequences", Proteins: Structure, Function,
Bioinformatics, Volume 64: pp.587-600, 2006.
Jianjun Hu, Yifeng David Yang & Daisuke Kihara, "EMD: an ensemble algorithm for discovering
regulatorymotifs in DNA sequences", BMC Bioinformatics, 7:342. (2006).
Funding Administered by Computer Science
Barry Wanner, Walid Aref, Daisuke Kihara, Michael Gribskov, and Xiang Zhang, Development of the
www.ecoli-community.org Information Resource, National Institutes of Health, 6/1/2006-5/31/2009.
Daisuke Kihara, Bayesian Models and Monte Carol Strategies in Identifying Protein or DNA Sequence
Motifs, National Science Foundation, 7/1/2006-6/30/2009.
Daisuke Kihara and Karthik Ramani, Surface Shape Based Screening of Large Protein Databases
PHS-NIH NAT INST of General Medical Science, National Institutes of Health, 9/30/2005-8/31/2010.
Last Updated: March 12, 2008 03:19pm
